CRBN抗原;Cereblon蛋白重组蛋白多种属是一种442个氨基酸的蛋白质,在人脑组织中高度集中。CRBN功能被认为与能量代谢、学习和记忆有关。CRBN定位于细胞质,在线粒体中充当蛋白酶,被认为调节KCNT1的组装,以及已知影响记忆和学习的大脑区域(如海马)中KCNT1表面的表达。编码CRBN的基因属于ATP依赖性lon蛋白酶家族,在膜运输和蛋白水解中发挥作用。CRBN基因
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品牌 | 上海信裕生物科技有限公司 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 90% |
分子量 | 18.4kDa | 货号 | XY90924RPHu01 |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Cereblon (CRBN)
Cereblon蛋白(CRBN)重组蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues: Lys300~Glu430
Tags: N-terminal His Tag
Subcellular Location: Membrane, Nucleus, Cytoplasm
Purity: > 90%
Traits: Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration: 300µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 8.3
Predicted Molecular Mass: 18.4kDa
Accurate Molecular Mass: 20kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
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