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胞质分裂作用因子4(DOCK4)重组蛋白 是一种细胞质外周膜蛋白,属于DOCK家族的胞质分裂调节蛋白。DOCK 4在前列腺、卵巢和骨骼肌中普遍表达,表达量最高,作为鸟嘌呤核苷酸交换因子(GEF)发挥作用,激活小GTP酶Rap 1,并通过这种激活在细胞间粘附连接的调节中发挥作用。与其他DOCK家族成员类似,DOCK 4包含一个N端SH3结构域、一个C端富含脯氨酸的区域和两个名为DHR1和
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品牌 | 信裕生物 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 97% |
分子量 | 17.4kDa | 货号 | XY93943RPHu01 |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Dedicator Of Cytokinesis 4 (DOCK4)
胞质分裂作用因子4(DOCK4)重组蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues: Met1~Pro300
Tags: N-terminal His Tag
Subcellular Location: Membrane, Cytoplasm
Purity: > 80%
Traits: Freeze-dried powder
Buffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Original Concentration: 200µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 8.9
Predicted Molecular Mass: 38.7kDa
Accurate Molecular Mass: 39kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do notvortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
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