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儿茶酚-O-甲基转移酶(COMT)重组蛋白 邻苯二酚-O-甲基转移酶催化甲基从S-腺苷甲硫氨酸转移到儿茶酚胺,包括神经递质多巴胺、肾上腺素和去甲肾上腺素。这种O-甲基化导致儿茶酚胺递质的主要降解途径之一。除了在内源性物质代谢中的作用外,COMT在用于治疗高血压、哮喘和帕金森病的邻苯二酚药物代谢中也很重要。COMT在组织中有两种形式,可溶性形式(S-COMT)和膜结合形式(MB-COMT)。S-CO
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品牌 | 上海信裕生物科技有限公司 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 97% |
分子量 | 25.6kDa | 货号 | XY90846RPHu01 |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Catechol-O-Methyltransferase (COMT)
儿茶酚-O-甲基转移酶(COMT)重组蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues: Gly52~Pro271
Tags: N-terminal His Tag
Subcellular Location: Membrane
Purity: > 97%
Traits: Freeze-dried powder
Buffer formulation: 20mM Tris, pH8.0, containing 0.01% skl, 5%Trehalose.
Original Concentration: 500µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 5.6
Predicted Molecular Mass: 25.6kDa
Accurate Molecular Mass: 26kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in ddH2O to a concentration ?0.1mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!以实际收货产品说明书为准,网站说明书仅供参考!
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