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核因子κB受体激活因子(RANk)重组蛋白 该基因编码的蛋白质是TNF受体超家族的成员。这种受体可以与各种TRAF家族蛋白相互作用,通过这种受体诱导NF-κB和MAPK8/JNK的激活。这种受体及其配体是T细胞和树突状细胞相互作用的重要调节因子。这种受体也是破骨细胞和淋巴结发育的重要介质。该位点的突变与家族性膨胀性骨溶解症、常染色体隐性骨硬化症和佩吉特骨病有关。或者,已经描述了该基因座的剪接转录变
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品牌 | 上海信裕生物科技有限公司 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 97% |
分子量 | 33.9kDa | 货号 | XY94317RPHu01 |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)
核因子κB受体激活因子(RANk)重组蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues: Val330~Lys615
Tags: N-terminal His Tag
Subcellular Location: Membrane
Purity: > 97%
Traits: Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration: 50µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 4.8
Predicted Molecular Mass: 33.9kDa
Accurate Molecular Mass: 44kDa as determined by SDS-PAGE reducing conditions.
Phenomenon explanation:
The possible reasons that the actual band size differs from the predicted are as follows:
1.Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affects the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleavedto give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
[ USAGE ]
Reconstitute in ddH2O to a concentration of 0.1-0.2 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
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