Articles
KLb抗原;可罗索β(KLb)重组蛋白多种属 BetaKlotho是一种1044个氨基酸的单程III型膜蛋白,通过抑制胆汁酸合成中的限速酶CYP7A1(胆固醇7-α-羟化酶)的转录,在胆汁酸和胆固醇代谢中起着关键作用。纯合阴性betaKlotho小鼠显示胆汁酸合成和分泌显著升高,CYP7A1和CYP8B1强烈上调,对胆结石形成具有抵抗力。FGF19和FGF21需要与betaKlotho直接相互作用
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品牌 | 上海信裕生物科技有限公司 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 95% |
分子量 | 15.1kDa | 货号 | XY92868RPHu01 |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Klotho Beta (KLb)
可罗索β(KLb)重组蛋白
[ PROPERTIES ]
Source:Prokaryotic expression
Host: E.coli
Residues:Val517~Ser636
Tags:N-terminal His Tag
Subcellular Location: Membrane
Purity: > 95%
Traits:Freeze-dried powder
Buffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Original Concentration:500µg/mL
Applications:Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point:9.4
Predicted Molecular Mass:15.1kDa
Accurate Molecular Mass:15kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do notvortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!以实际收货产品说明书为准,网站说明书仅供参考!
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