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LTBP1抗原;LTBP1重组蛋白多种属 潜在转化生长因子β1结合蛋白1(LTBP-1)是一种重糖蛋白,是血小板衍生的TGF-β1复合物的一部分。LTBP-1作为细胞外基质中潜在TGF-β的锚定物,是微纤维结构的一个组成部分。LTBP的切割产生LTBP-1,它可能将潜在的TGF-β隔离在细胞外基质中并调节其激活。LTBP-1 mRNA在卵巢癌组织中富集,在浆液性和粘液性腺癌中高度表达。
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品牌 | 信裕生物 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 95% |
分子量 | 37.5kDa | 货号 | XY92909RPHu01 |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1)
组织内转化生长因子β结合蛋白1(LTBP1)重组蛋白
[ PROPERTIES ]
Source:Prokaryotic expression
Host: E.coli
Residues: Asp1424~Glu1721
Tags:N-terminal His Tag
Subcellular Location: Secreted
Purity: > 95%
Traits:Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration:200µg/mL
Applications:Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point:4.2
Predicted Molecular Mass: 37.5kDa
Accurate Molecular Mass: 44kDa as determined by SDS-PAGE reducing conditions.
Phenomenon explanation:
The possible reasons that the actual band size differs from the predicted are as follows:
1.Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affects the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleavedto give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
[ USAGE ]
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
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