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线粒体蛋白酪氨酸磷酸酶1(PTPMT1)重组蛋白

线粒体蛋白酪氨酸磷酸酶1(PTPMT1)重组蛋白 TPMT是硫嘌呤类药物(如硫唑嘌呤、巯嘌呤和硫鸟嘌呤)的代谢中最主要的酶之一,起到的作用是在这类化合物的硫原子上增加一个甲基;这个过程中提供甲基的是S-腺苷甲硫氨酸,后者同时被转化成S-腺苷-L-高半胱氨酸。 TPMT基因的缺陷会让人体无法将这类药物灭活,未代谢的药物因此在体内大量累积,从而引起严重甚至致命的骨髓抑制,表现为贫血、血小板减少症(导致

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  • 更新时间:2025-01-26
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详细介绍
品牌上海信裕生物科技有限公司CAS详见说明书
分子式详见说明书纯度> 95%
分子量26.9kDa货号XY94203RPHu
规格50µg/100µg供货周期一周
主要用途SDS-PAGE; WB应用领域生物产业

Recombinant Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1) 

线粒体蛋白酪氨酸磷酸酶1(PTPMT1)重组蛋白

[ PROPERTIES ]

Source:Prokaryotic expression

Host: E.coli

Residues: Leu26~His227

Tags:N-terminal His Tag

Tissue Specificity: Kidney, Bone marrow, Cervix carcinoma, Liver.

Subcellular Location: Cytoplasm

Purity: > 95%

Traits:Freeze-dried powder

Buffer formulation: 100mM NaHCO3, 500mM NaCl, pH8.3, containing1mMEDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.

Original Concentration:200µg/mL

Applications:Positive Control; Immunogen; SDS-PAGE; WB.

(May be suitable for use in other assays to be determined by the end user.)

Predicted isoelectric point:6.7

Predicted Molecular Mass: 26.9kDa

Accurate Molecular Mass: 27kDa as determined by SDS-PAGE reducingconditions

[ USAGE ]

Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentrationof0.1-1.0 mg/mL. Do not vortex.

[ STORAGE AND STABILITY ]

Storage: Avoid repeated freeze/thaw cycles.

           Store at 2-8ºC for one month.

           Aliquot and store at -80ºC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

[SEQUENCE ]

线粒体蛋白酪氨酸磷酸酶1(PTPMT1)重组蛋白

[  IDENTIFICATION  ]

线粒体蛋白酪氨酸磷酸酶1(PTPMT1)重组蛋白

[ IMPORTANT NOTE ]

The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.

特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!以实际收货产品说明书为准,网站说明书仅供参考!




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