Articles
线粒体蛋白酪氨酸磷酸酶1(PTPMT1)重组蛋白 TPMT是硫嘌呤类药物(如硫唑嘌呤、巯嘌呤和硫鸟嘌呤)的代谢中最主要的酶之一,起到的作用是在这类化合物的硫原子上增加一个甲基;这个过程中提供甲基的是S-腺苷甲硫氨酸,后者同时被转化成S-腺苷-L-高半胱氨酸。 TPMT基因的缺陷会让人体无法将这类药物灭活,未代谢的药物因此在体内大量累积,从而引起严重甚至致命的骨髓抑制,表现为贫血、血小板减少症(导致
联系电话:15221858802
品牌 | 上海信裕生物科技有限公司 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 95% |
分子量 | 26.9kDa | 货号 | XY94203RPHu |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1)
线粒体蛋白酪氨酸磷酸酶1(PTPMT1)重组蛋白
[ PROPERTIES ]
Source:Prokaryotic expression
Host: E.coli
Residues: Leu26~His227
Tags:N-terminal His Tag
Tissue Specificity: Kidney, Bone marrow, Cervix carcinoma, Liver.
Subcellular Location: Cytoplasm
Purity: > 95%
Traits:Freeze-dried powder
Buffer formulation: 100mM NaHCO3, 500mM NaCl, pH8.3, containing1mMEDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
Original Concentration:200µg/mL
Applications:Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point:6.7
Predicted Molecular Mass: 26.9kDa
Accurate Molecular Mass: 27kDa as determined by SDS-PAGE reducingconditions
[ USAGE ]
Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentrationof0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!以实际收货产品说明书为准,网站说明书仅供参考!
电话