Articles
BRCC3抗原;BRCC3重组蛋白多种属 特异性切割“Lys-63"连接的多泛素链的金属蛋白酶。对“Lys-48"连接的多泛素链没有活性。BRCA1-A复合物的组成部分,该复合物在DNA损伤位点特异性识别“Lys-63"连接的泛素化组蛋白H2A和H2AX,从而将BRCA1-BARD1异二聚体靶向双链断裂(DSBs)处的DNA损伤位点。在BRCA1-A复合物中,它特异性地去除组蛋白H2A和H2AX上
联系电话:15221858802
品牌 | 信裕生物 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 95% |
分子量 | 19.8kDa | 货号 | XY90651RPHu |
供货周期 | 一周 | 主要用途 | SDS-PAGE; WB; ELISA; IP. |
应用领域 | 生物产业 |
Recombinant BRCA1/BRCA2 Containing Complex Subunit 3 (BRCC3)
含BRCA1/BRCA2复合体3亚基(BRCC3)重组蛋白
[ PROPERTIES ]
Residues: Gln7~Gly148
Tags: Two N-terminal Tags, His-tag and T7-tag
Accession: P46736
Host: E. coli
Subcellular Location: Nucleus
Purity: >95%
Endotoxin Level: <1.0EU per 1μg
(determined by the LAL method).
Formulation: Supplied as lyophilized form in 20mM Tris,150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT,0.01% sarcosyl, 5% trehalose, and preservative.
Predicted isoelectric point: 5.9
Predicted Molecular Mass: 19.8kDa
Applications: SDS-PAGE; WB; ELISA; IP.
(May be suitable for use in other assays to be determined by the end user.)
[ USAGE ]
Reconstitute in sterile ddH2O.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
The sequence of the target protein is listed below.
QAVQ AVHLESDAFL VCLNHALSTE KEEVMGLCIG ELNDDTRSDS KFAYTGTEMRTVAEKVDAVR IVHIHSVIIL RRSDKRKDRV EISPEQLSAA STEAERLAEL TGRPMRVVGWYHSHPHITVW PSHVDVRTQA MYQMMDQG
[ IDENTIFICATION ]
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!以实际收货产品说明书为准,网站说明书仅供参考!
电话