Articles
CLDN6抗原;封闭蛋白6重组蛋白多种属 紧密连接代表了上皮或内皮细胞片中细胞间粘附的一种模式,在细胞周围形成连续的密封,并作为物理屏障,防止溶质和水自由通过细胞旁空间。这些连接由面向外的细胞质小叶中的连续网络链组成,面向内的细胞质外小叶中有互补的凹槽。该基因编码紧密连接链的一个组成部分,它是claudin家族的成员。该蛋白是一种完整的膜蛋白,是丙型肝炎病毒的进入辅因子之一。基因甲基化可能与食管肿
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品牌 | 上海信裕生物科技有限公司 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 95% |
分子量 | 19.6kDa | 货号 | XY91052RPHu |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Claudin 6 (CLDN6)
封闭蛋白6(CLDN6)重组蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues: Met29~Arg81
Tags: Two N-terminal Tags, His-tag and SUMO-tag
Subcellular Location: Membrane
Purity: > 95%
Traits: Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration: 6000µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 6.3
Predicted Molecular Mass: 19.6kDa
Accurate Molecular Mass: 23kDa as determined by SDS-PAGE reducing conditions.
Phenomenon explanation:
The possible reasons that the actual band size differs from the predicted are as follows:
1.Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affects the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleavedto give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
[ USAGE ]
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!以实际收货产品说明书为准,网站说明书仅供参考!
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