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甲基CpG结合域蛋白1(MBD1)重组蛋白 DNA甲基化,或在二核苷酸CpG中胞嘧啶碱基上添加甲基,对于正常发育和调节基因表达至关重要。甲基化模式涉及甲基化和去甲基化的酶过程。最近发现脱甲基化酶是一种哺乳动物蛋白质,其表现出与甲基CpG结合结构域(MBD)相关的脱甲基酶活性。该酶能够通过催化甲基裂解为甲醇,将甲基化胞嘧啶碱基还原为特定二核苷酸序列mdCpdG中的胞嘧啶。MeCP2和MBD1(PCM
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品牌 | 上海信裕生物科技有限公司 | CAS | 详见说明书 |
---|---|---|---|
分子式 | 详见说明书 | 纯度 | > 95% |
分子量 | 27.6kDa | 货号 | XY93192RPHu |
规格 | 50µg/100µg | 供货周期 | 一周 |
主要用途 | SDS-PAGE; WB | 应用领域 | 生物产业 |
Recombinant Methyl CpG Binding Domain Protein 1 (MBD1)
甲基CpG结合域蛋白1(MBD1)重组蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues:Met1~Leu216
Tags: N-terminal His Tag
Subcellular Location: Nucleus
Purity: > 95%
Traits: Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration: 400µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 9.3
Predicted Molecular Mass: 27.6kDa
Accurate Molecular Mass: 28kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!以实际收货产品说明书为准,网站说明书仅供参考!
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